This article won't show you all the possible settings in Thunderbird, because there are so many. Thunderbird is one of the most powerful & flexible email clients available at the time of writing, especially if you use IMAP4 (with VPOP3 Enterprise).
The instructions below are for Thunderbird version 3.0, but the settings should be similar in later versions. Earlier versions just have a manual setup procedure, so you can skip some of the steps below.
Note that the below settings are only suggestions, and there are many other ways you may want to set things up, but these are a good starting point.
If you want Thunderbird to be able to access the VPOP3 LDAP service: