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The VPOP3 Status Monitor is the program which shows the little (usually red) postbox icon in the Windows task tray. This usually launches automatically from the Windows startup group. This program is VPOP3Status.EXE on the disk, or can be run manually from Start → Programs → VPOP3 → VPOP3 Monitor in Windows.
The status monitor talks to VPOP3 using TCP/IP, usually using port 5109, and it has to log into VPOP3 as a user, so different users can be configured to access different features through the status monitor. Therefore, you should be able to the status monitor from any computer on your network.
If you have multiple status monitor icons in the task tray, this does not mean that VPOP3 is running several times, just that the VPOP3 Status Monitor has been started several times. Sometimes this can happen if it has been added to the 'All Users' Startup group as well as your personal Startup group in Windows.
How you remove the duplicate icon depends on the version of Windows you are using.
In Windows 7, press the Start button, go to All Programs, then find the Startup group. Right-click it and choose 'Explore All Users'. This will show the list of startup items in the 'All Users' group, rather than your personal group. Remove the VPOP3 Monitor shortcut from there.